Posts tagged hippocampus
Mobile chunks of DNA that walk their way from one position in the genome to another may affect neurological diseases and could have subtle influences on normal brain function and behavior, according to a recent study in Nature.
Alu is an example of a so-called “jumping gene” – a transposable DNA sequence that “reproduces” by copying itself and inserting into new locations throughout the genome. Alu elements are classified as SINEs, or Short INterspersed Elements. All Alus are approximately 300 bp in length and derive their name from a single recognition site for the restriction enzyme AluI located near the middle of the Alu More >
Alzheimer’s disease is a debilitating disease where neurons in the brain die. These neurons are called basal forebrain cholinergic neurons and their job is to help the hippocampus retrieve memories in the brain. Alzheimer’s disease patients do not have the ability to retrieve memories. It’s not that those memories are lost, they just cannot be retrieved. In early Alzheimer’s, these special neurons die. Since there are so few to be found within the brain, their death can quickly become devastating.
Northwestern Medicine researchers have made a major discovery that can aid in understanding and treating Alzheimer’s. These researchers have taken human More >