Posts tagged drugs
Just like normal tissue, tumors need blood vessels to grow. Because of this, drugs that stop angiogenesis, or the formation of new blood vessels, are one important approach to treating cancers. These angiogenesis inhibitors stop tumor growth by starving them of oxygen and nutrients, usually by interfering with signals from the tumor cells that promote blood vessel formation in the surrounding tissue. Angiogenesis inhibitors have been shown to be effective in the treatment of several cancer types, but the results aren’t always as expected. Several recent studies show how complicated this can be. For instance, FDA approval of the drug More >
This morning, “Good Morning America,” a popular morning news program in the U.S. told the story of a mother with an autistic child who was “treating” him with marijuana. I use quotation marks, and will make other cautionary notes here, because this blog is not meant to represent any forum of medical advice.
At the time of writing this, the GMA website, which usually posts follow-ups, has nothing on their site, which I found a little strange. The mother also appeared not with another member of her family, but a lawyer, who was also a family friend. I wondered how these More >
In the emerging field of pharmacogenetics, scientists study genome variations and correlate them with drug treatment response. For example, variations (also called polymorphisms) in genes encoding enzymes involved in drug metabolism have been found to affect the activation, deactivation, and toxicity of drugs used to treat cancer, heart disease, and psychiatric disorders. Recently, scientists found that DNA sequence can also be used to predict responsiveness to current Hepatitis C treatment (a More >
As the ongoing deciphering of the human genome provides us with more and more insights about our predisposition for diseases and genetic disorders, (see Your Genes Your Health for examples) I am equally, if not more astounded by what it tells us about our ability to utilize medicines to counteract diseases.
Just recently, a group of researchers at the University of Maryland School of Medicine have identified a variant of a gene that is believed to play a major role in determining why people do not respond to a popular anti-clotting medication. This gene variant, carried by as many as a third More >