Posts tagged telomerase
It might be more real than not. Scientists working at the biotech giant Geron Corporation have isolated a molecule, TA-65, which has the ability to increase telomerase activity (It is important to note that his find has not been evaluated in published peer reviewed studies as of yet). This is an exciting breakthrough for telomerase is an enzyme that adds DNA sequence repeats to the 3′ end of DNA strands in the telomere regions, which are found at the ends of eukaryotic chromosomes. The telomeres contain condensed DNA material, giving stability to the chromosomes. These telomere DNA sequences shorten with More >
I was always under the impression that sharks never got cancer. It turns out that isn’t true – they do get cancer, but less often than people. There is an animal that doesn’t get cancer though, and that is the naked mole rat. These cute little creatures live long lives underground, so I’m not sure how anyone figured this out.
Needless to say, an animal that doesn’t get cancer is something worth studying. Why no cancer? It turns out that mole rat cells don’t “like” each other very much. Researchers discovered that when these cells are cultured, they stop dividing at More >
Nobel Prize week kicked-off today with the announcement of the Prize in Physiology or Medicine. As predicted on these pages, Elizabeth Blackburn, Carol Greider, and Jack Szostak shared the award for discovering telomeres and telomerase. This is particularly good news for Cold Spring Harbor Laboratory, which was home to Carol Greider when she made the pivotal discovery of isolating the RNA gene that encodes for the telomeric template.
What is a Telomere? A telomere is a region (or cap) of repetitive DNA at the end of every chromosome that basically More >
Nobel Prize week will kick-off on Monday (October 5th) with the announcement of the Prize in Physiology or Medicine. The prizes for Physics and Chemistry will follow on successive days, as the science world is treated to its annual brush with celebrity. Unlike the Oscars, however, we do not know the list of nominees and the whole election process is rather secretive. Deprived as we are of a list of formal candidates, I think it best to resort to wild speculation, conjecture, and rumor.
Physiology and Medicine…
The main contenders: Elizabeth Blackburn, Carol Greider, and (possibly) Jack Szostak The discovery: Telomeres and telomerase More >