Posts tagged Pharmacogenetics
In the emerging field of pharmacogenetics, scientists study genome variations and correlate them with drug treatment response. For example, variations (also called polymorphisms) in genes encoding enzymes involved in drug metabolism have been found to affect the activation, deactivation, and toxicity of drugs used to treat cancer, heart disease, and psychiatric disorders. Recently, scientists found that DNA sequence can also be used to predict responsiveness to current Hepatitis C treatment (a More >
As the ongoing deciphering of the human genome provides us with more and more insights about our predisposition for diseases and genetic disorders, (see Your Genes Your Health for examples) I am equally, if not more astounded by what it tells us about our ability to utilize medicines to counteract diseases.
Just recently, a group of researchers at the University of Maryland School of Medicine have identified a variant of a gene that is believed to play a major role in determining why people do not respond to a popular anti-clotting medication. This gene variant, carried by as many as a third More >