Posts tagged neurodegenerative diseases
Trying to unlock a new door…..
Nov 28th
How is drug development moving along? Well, this is a very good question for we are still plagued by some elusive diseases, cancer for example. There have been many drugs developed targeting proteins involved in disease states some of which have proven to be quite effective. However today the steam engine for identifying drug targets to proteins involved in disease is becoming ever more difficult. Apparently over the past decade or so, the number of new drugs targeted toward disease has declined. This is primarily due to the fact that developing new medicine has become more difficult to do. It More >
Will insulin come to the rescue of AD patients?
Sep 27th
Alzheimer disease (AD) is a neurodegenerative disease of the brain that is divided into early- and late-onset groups. AD is characterized by the build up of amyloid plaques, neurofibrillary tangles and the loss of connections between neurons. It is the most common type of dementia especially in the elderly. The exact causes of AD are elusive at the moment but are most likely the result of genetics and other factors. Scientist have been working hard to identify individual and or groups of genes responsible for the disease. Although the scientific community has identified may genes involved in early and late More >
RBD and Neurodegeneration
Sep 2nd
In an earlier post I blogged about the nature of dreams including phases of sleep and why we dream. In the blog I had mentioned a sleep disorder known as REM sleep behavior disorder (or RBD). It’s a mysterious sleep disturbance where the normal atonia (muscle paralysis) during sleep malfunctions, and the dreamer is left to act out their dreams. Those with this disorder (predominantly male) tend to have dreams that are increasingly violent and involve fighting off an attacker. In their sleep, these people act out every punch, kick, twist and scream with their sleeping bodies, often times injuring More >