The fourth most common and second leading cause of cancer-related death around the world is gastric cancer. It is estimated that the world standardized incidence of gastric cancer is about 16.2/100,000 persons per year. The only prognosis method for gastric cancer is the International Union Against Cancer Tumor-Node-Metastasis (TMN) staging system, in which the degree of tumor penetration and nodal status are the two main prognostic indicators in patients without distant metastatic disease. It turns out that surgery is an option for early stage patients, but 50% of gastric cancer patients suffer from tumor relapse even after radical surgery. Hence, More >