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	<title>DNALC Blogs &#187; skin</title>
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		<title>Addicted to the Tan</title>
		<link>http://blogs.dnalc.org/2011/08/22/addicted-to-the-tan/</link>
		<comments>http://blogs.dnalc.org/2011/08/22/addicted-to-the-tan/#comments</comments>
		<pubDate>Mon, 22 Aug 2011 16:17:12 +0000</pubDate>
		<dc:creator><![CDATA[Jennifer Aiello]]></dc:creator>
				<category><![CDATA[G2C Online]]></category>
		<category><![CDATA[addicted]]></category>
		<category><![CDATA[melanin]]></category>
		<category><![CDATA[melanocytes]]></category>
		<category><![CDATA[skin]]></category>
		<category><![CDATA[tan]]></category>
		<category><![CDATA[tanning]]></category>
		<category><![CDATA[ultra violet]]></category>
		<category><![CDATA[UV]]></category>

		<guid isPermaLink="false">http://blogs.dnalc.org/?p=3819</guid>
		<description><![CDATA[Tanning is dangerous. Most people know this, yet why is it continuously something many cannot avoid? It has been known for a long time that UV rays damage DNA and can lead to skin cancer, including melanoma, premature aging and wrinkles. 120,000 new melanoma cases are diagnosed every year.  A 2005 study showed that 92%&#8230;]]></description>
				<content:encoded><![CDATA[<p><a href="http://blogs.dnalc.org/wp-content/uploads/2011/08/tanning-bed1-150x150.jpg"><img class="alignleft size-full wp-image-3821" src="http://blogs.dnalc.org/wp-content/uploads/2011/08/tanning-bed1-150x150.jpg" alt="" width="150" height="150" /></a>Tanning is dangerous. Most people know this, yet why is it continuously something many cannot avoid? It has been known for a long time that UV rays damage DNA and can lead to skin cancer, including melanoma, premature aging and wrinkles. 120,000 new melanoma cases are diagnosed every year.  A 2005 study showed that 92% of people knew the sun was dangerous but 62% of them still loved to tan. Over 30 million Americans visit tanning salons, as much as 1 million a day. 70% of them are women between the ages of 16 and 49.</p>
<p>Tanning is dangerous because it requires the increase of UV radiation exposure in order to produce a tan. A tan is created due to melanogenesis of melanocytes. Melanocytes are skin cells that produce the protein melanin. We produce melanin which creates our skin color. When our skin cells are exposed to UV rays, the DNA of those melanocytes is affected and damaged. This damage creates the development of a tan.</p>
<p><a href="http://blogs.dnalc.org/wp-content/uploads/2011/08/sunburn1-150x150.jpg"><img class="size-full wp-image-3820 alignright" src="http://blogs.dnalc.org/wp-content/uploads/2011/08/sunburn1-150x150.jpg" alt="" width="150" height="150" /></a>Direct DNA damage due to UV radiation can be seen with a sunburn and by the increased production of melanin (or a tan). Too much of this direct DNA damage will give a painful warning signal- heat and the eventual painful sunburn.</p>
<p>In comparison, indirect DNA damage does not cause a tan or sunburn and there is no painful warning signal. Instead, the radiation creates free radicals which can affect surrounding cells.</p>
<p>So why do so many people go to tanning salons or sit for hours under the sun’s rays? Why do some people install home tanning beds? For many young people, media might play a role. The show Jersey Shore has a motto “GTL- Gym, Tanning, Laundry”. Tanning is a regular occurrence. Why? Because “it makes you look good” as some of the cast explained. But at what cost?</p>
<p>Scientists have studied why some people are “addicted” to the tan. As it turns out, tanning causes brain activity changes that are similar in those seen in people addicted to drugs and alcohol. Tanning causes an addictive neurological reward and reinforcement trigger according to the UT Southwestern Medical Center. The study involved 2 groups of people. One group tanned which the scientists measured brain activity. The other group also tanned, but there UV radiation was filtered out. The group that tanned with full radiation showed more brain activity than the filtered group. When asked about how satisfied they felt about their tanning experience, the group that had the filter expressed that their desire to tan was as high as it was before tanning.</p>
<p>So knowing the dangers of tanning might not be enough to deter people from doing it. Despite the safer alternative (tanning spray) it might be harder to get people choose that option over the more addictive one.</p>
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		<title>Genetic Codes for Skin and Lung Cancer have been Busted!</title>
		<link>http://blogs.dnalc.org/2009/12/22/genetic-codes-for-skin-and-lung-cancer-have-been-busted/</link>
		<comments>http://blogs.dnalc.org/2009/12/22/genetic-codes-for-skin-and-lung-cancer-have-been-busted/#comments</comments>
		<pubDate>Tue, 22 Dec 2009 16:44:51 +0000</pubDate>
		<dc:creator><![CDATA[Elna Carrasco]]></dc:creator>
				<category><![CDATA[DNA Interactive]]></category>
		<category><![CDATA[Cancer]]></category>
		<category><![CDATA[Genome]]></category>
		<category><![CDATA[lung]]></category>
		<category><![CDATA[Research]]></category>
		<category><![CDATA[skin]]></category>

		<guid isPermaLink="false">http://6.126</guid>
		<description><![CDATA[&#8220;Cancer is a leading cause of death worldwide and claims more than 7 million lives each year according to the World Health Organization.&#8221; Cancer cells have mutations in their genes that render them unable to respond to signals that regulate cell division. These cells grow uncontrollably and can invade normal tissue in other locations of&#8230;]]></description>
				<content:encoded><![CDATA[<p><a href="http://blogs.dnalc.org/wp-content/uploads/2009/12/Cancer.jpg"><img class="alignleft size-full wp-image-3263" title="Cancer" src="http://blogs.dnalc.org/wp-content/uploads/2009/12/Cancer.jpg" alt="" width="146" height="131" /></a>&#8220;Cancer is a leading cause of death worldwide and <a href="http://www.cnn.com/2009/HEALTH/12/17/cancer.research.breakthrough.genetic/">claims more than 7 million lives each year</a> according to the <a href="http://www.who.int/topics/cancer/en/">World Health Organization</a>.&#8221;</p>
<p><a href="http://www.insidecancer.org/">Cancer cells have mutations in their genes that render them unable to respond to signals that regulate cell division</a>. These cells grow uncontrollably and can invade normal tissue in other locations of the body and cause disrupted functions of major organs. This is why cancer is so deadly.</p>
<p>A mutagen is a physical or chemical substance that can alter genetic material in cells. DNA can be damaged or changed (mutated).   Cancer cells have changes in the genes themselves. These changes can include mutations , deletions of part or whole genes or even the addition of extra copies of genes.</p>
<p>There are many mutagens that can cause cancer in cells. These are called carcinogens. Two of the most common and most deadly cancers, lung and skin are caused by two well known carcinogens, cigarette smoke and sunlight. Some studies suggest <a href="http://www.mnn.com/lifestyle/health/stories/cigarettes-mutate-smokers-genes">when 15 cigarettes are smoked, an error in DNA occurs</a>.</p>
<p>Now the UK’s Wellcome Trust Sanger Institute has <a href="http://www.sanger.ac.uk/genetics/CGP/">cracked the code for the mutations within DNA that can cause tumors </a>that lead to these two devastating types of cancers.</p>
<p>This new information can open the door to major advancements in treatment, medication and maybe even cures in the future of skin and lung cancers.</p>
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