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	<title>DNALC Blogs &#187; diet</title>
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	<link>http://blogs.dnalc.org</link>
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		<title>Controlling gene expression through diet</title>
		<link>http://blogs.dnalc.org/2012/02/16/controlling-gene-expression-through-diet/</link>
		<comments>http://blogs.dnalc.org/2012/02/16/controlling-gene-expression-through-diet/#comments</comments>
		<pubDate>Thu, 16 Feb 2012 14:30:43 +0000</pubDate>
		<dc:creator><![CDATA[Jermel Watkins]]></dc:creator>
				<category><![CDATA[Your Genes, Your Health]]></category>
		<category><![CDATA[agouti]]></category>
		<category><![CDATA[Cancer]]></category>
		<category><![CDATA[diet]]></category>
		<category><![CDATA[dna]]></category>
		<category><![CDATA[Epigenetics]]></category>
		<category><![CDATA[epigenetics & nutrition]]></category>
		<category><![CDATA[Inheritance]]></category>
		<category><![CDATA[Methylation]]></category>
		<category><![CDATA[obesity]]></category>
		<category><![CDATA[variable regulation]]></category>

		<guid isPermaLink="false">http://blogs.dnalc.org/?p=4533</guid>
		<description><![CDATA[Epigenetics is the study of chemical reactions that control the on and off switch of genes at specific times and the factors influencing them. Environment is a factor that influences epigenetic change which may encompass behavior, stress or diet. The easiest of the three to make observations from is diet. When we think of food,&#8230;]]></description>
				<content:encoded><![CDATA[<p><a href="http://blogs.dnalc.org/wp-content/uploads/2012/02/1-dna-strands.jpg"><img class="alignleft size-medium wp-image-4534" src="http://blogs.dnalc.org/wp-content/uploads/2012/02/1-dna-strands-300x225.jpg" alt="" width="300" height="225" /></a>Epigenetics is the study of chemical reactions that control the on and off switch of genes at specific times and the factors influencing them.  Environment is a factor that influences epigenetic change which may encompass behavior, stress or diet.  The easiest of the three to make observations from is diet.  When we think of food, rarely do we think of chemical modifications to DNA and restriction of gene activity. Commonly we think of foods coming in and being broken down into nutrients to be utilized in metabolic pathways to make components the body can use.  Interestingly one of the pathways utilized produces methyl groups, the chemical (epigenetic) tags used to shut off genes.  Research has shown that diets rich in methyl donating nutrients in early development and as an infant can cause lasting changes.</p>
<p>Well what do I mean by lasting changes?  Research has shown that depending on what your mother eats may influence your genes and health in the long run.  The gene agouti is found in humans and mice.  The agouti/melanocortin system is an important regulator of body weight homeostasis.  Mouse studies have shown that when the agouti gene is not methylated the result is obese yellow coated mice which may be at risk for cancer and diabetes.  When the gene is methylated mice are brown, of normal weight and size.  The only difference between the two types of mice is the methylation control on the agouti gene.  In parallel experiments were carried out where yellow female mice were fed a methyl enriched diet; the offspring grew to be normal weight, size and were brown in color and remained so for the rest of their adulthood.  This study identified that an individual’s wellbeing is not only determined by what they eat but also what their parents ate.</p>
<p>References<br />
Nutrition and the epigenome. Retrieved February 8, 2012, from http://learn.genetics.utah.edu/content/epigenetics/nutrition/</p>
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		<title>Six Tips on Avoiding Cancer</title>
		<link>http://blogs.dnalc.org/2009/11/30/six-tips-on-avoiding-cancer/</link>
		<comments>http://blogs.dnalc.org/2009/11/30/six-tips-on-avoiding-cancer/#comments</comments>
		<pubDate>Mon, 30 Nov 2009 10:43:03 +0000</pubDate>
		<dc:creator><![CDATA[admin]]></dc:creator>
				<category><![CDATA[Inside Cancer]]></category>
		<category><![CDATA[Cancer]]></category>
		<category><![CDATA[diet]]></category>
		<category><![CDATA[food]]></category>
		<category><![CDATA[fruit]]></category>
		<category><![CDATA[meat]]></category>
		<category><![CDATA[Prevention]]></category>
		<category><![CDATA[smoking]]></category>
		<category><![CDATA[vegetables]]></category>
		<category><![CDATA[weight]]></category>

		<guid isPermaLink="false">http://blogs.dnalc.org/?p=3655</guid>
		<description><![CDATA[Most of us know that smoking cigarettes and excess exposure to the sun can increase the risk of getting cancer. In fact, much of cancer can be avoided by changing behavior. For examples of some causes of cancer, check out Inside Cancer. Some of the causes of cancer are less obvious. An example is maintaining&#8230;]]></description>
				<content:encoded><![CDATA[<p><a href="http://blogs.dnalc.org/wp-content/uploads/2009/11/healthy_diet_150x150.jpg"><img class="alignleft size-full wp-image-3237" title="healthy_diet_150x150" src="http://blogs.dnalc.org/wp-content/uploads/2009/11/healthy_diet_150x150.jpg" alt="" width="150" height="150" /></a>Most of us know that smoking cigarettes and excess exposure to the sun can increase the risk of getting cancer. In fact, much of cancer can be avoided by changing behavior. For examples of some causes of cancer, check out <em><a href="http://www.insidecancer.org">Inside Cancer</a></em>. Some of the causes of cancer are less obvious. An example is maintaining a healthy weight. Did you know that overweight people are 50% more likely to die of cancer than those with normal body weight? In the United States, this means each year about 90,000 people die of cancer that could be prevented if we could all keep those extra pounds off.</p>
<p>The foods we eat also have a big effect. I think back on what my mother used to preach, and I think she had it right. She told me to eat my greens and have lots of fruit. On the other hand, somehow she knew too much alcohol, red meat, and sugary drinks are bad. &#8220;Where did all the ice cream go?&#8221; echoes from the past. My hiking and canoeing mother encouraged me to do sports and other outdoor activities. I knew these choices were healthy and protected me from heart disease. What I didn’t realize was that my mother was protecting me from cancer, too.</p>
<p>The <a href="http://www.wcrf.org/research/expert_report/recommendations.php">World Cancer Research </a>Fund has recommendations for how to prevent cancer. I think they interviewed my mom.</p>
<p>Here are some of them:<br />
•	Be as lean as possible in the normal range of body weight<br />
•	Be physically active every day<br />
•	Avoid &#8220;energy-dense&#8221; foods and sugary drinks.<br />
•	Eat lots of non-starchy veggies and fruit<br />
•	Limit red meat and processed meat in your diet<br />
•	Avoid salt</p>
<p>You can check out the details and see the whole list on their web site:</p>
<p><a href="http://www.wcrf.org/research/expert_report/recommendations.php">http://www.wcrf.org/research/expert_report/recommendations.php</a></p>
<p>Now that I have passed on my mother’s preaching, you have yet another reason to eat well and exercise. I’m off to the gym… to fight cancer and heart disease at the same time!</p>
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